High-Performance Liquid Chromatography (HPLC) is one of the most widely used analytical techniques, yet the theory underpinning liquid-phase separations is often poorly understood. This masterclass introduces participants to the important chemical factors that influence HPLC separations (including polarity, acid-base theory, and hydrogen bonding), chromatographic theory, troubleshooting, and method development/validation.
Each day ends with an interactive workshop session.
By the end of this three-day intensive course, you will:
You want to understand the theory behind liquid chromatography
You would like to understand how HPLC systems work
You would like to understand how HPLC systems work
You would like to improve your approach to HPLC method development
You would like to understand how problems can arise in the individual components of a HPLC system
You need to know how to approach HPLC method validation
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Dr Mark Powell is a Fellow of the Royal Society of Chemistry (RSC) with over thirty years’ experience as a senior analytical chemist. Mark has served as both Honorary Secretary and Honorary Treasurer of the RSC’s AnalyticalDivision and led a working group on continuing professional development until July 2016.
He has worked at a senior level in several companies with responsibility for analytical development and equipment qualification. In 2010 Mark was appointed Scientific Manager of a UK-based pharmaceutical CRO, with responsibility for guiding the direction of drug development programmes, including stability evaluation.
In 2013, he set up his own company to provide training and consultancy services to the pharmaceutical industry. His consultancy work has involved managing the analytical and stability aspects of early and late-stage pharmaceutical development programmes and conducting data integrity audits. He is in demand as a trainer in topics such as pharmaceutical development, chromatography, spectroscopy, dissolution testing, data integrity, control of impurities, technical writing, root cause analysis and stability/stress studies.
